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Transcriptional and post-transcriptional regulation of the ionizing radiation response by ATM and p53
In response to ionizing radiation (IR), cells activate a DNA damage response (DDR) pathway to re-program gene expression. Previous studies using total cellular RNA analyses have shown that the stress kinase ATM and the transcription factor p53 are integral components required for induction of IR-ind...
Autores principales: | Venkata Narayanan, Ishwarya, Paulsen, Michelle T., Bedi, Karan, Berg, Nathan, Ljungman, Emily A., Francia, Sofia, Veloso, Artur, Magnuson, Brian, di Fagagna, Fabrizio d’Adda, Wilson, Thomas E., Ljungman, Mats |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335570/ https://www.ncbi.nlm.nih.gov/pubmed/28256581 http://dx.doi.org/10.1038/srep43598 |
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