Cholesterol depletion impairs contractile machinery in neonatal rat cardiomyocytes

Cholesterol regulates numerous cellular processes. Depleting its synthesis in skeletal myofibers induces vacuolization and contraction impairment. However, little is known about how cholesterol reduction affects cardiomyocyte behavior. Here, we deplete cholesterol by incubating neonatal cardiomyocyt...

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Detalles Bibliográficos
Autores principales: Hissa, Barbara, Oakes, Patrick W., Pontes, Bruno, Ramírez-San Juan, Guillermina, Gardel, Margaret L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335656/
https://www.ncbi.nlm.nih.gov/pubmed/28256617
http://dx.doi.org/10.1038/srep43764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335656/
https://www.ncbi.nlm.nih.gov/pubmed/28256617
http://dx.doi.org/10.1038/srep43764

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