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Cholesterol depletion impairs contractile machinery in neonatal rat cardiomyocytes
Cholesterol regulates numerous cellular processes. Depleting its synthesis in skeletal myofibers induces vacuolization and contraction impairment. However, little is known about how cholesterol reduction affects cardiomyocyte behavior. Here, we deplete cholesterol by incubating neonatal cardiomyocyt...
Autores principales: | Hissa, Barbara, Oakes, Patrick W., Pontes, Bruno, Ramírez-San Juan, Guillermina, Gardel, Margaret L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335656/ https://www.ncbi.nlm.nih.gov/pubmed/28256617 http://dx.doi.org/10.1038/srep43764 |
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