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Limitations and challenges of genetic barcode quantification

Genetic barcodes are increasingly used to track individual cells and to quantitatively assess their clonal contributions over time. Although barcode quantification relies entirely on counting sequencing reads, detailed studies about the method’s accuracy are still limited. We report on a systematic...

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Detalles Bibliográficos
Autores principales: Thielecke, Lars, Aranyossy, Tim, Dahl, Andreas, Tiwari, Rajiv, Roeder, Ingo, Geiger, Hartmut, Fehse, Boris, Glauche, Ingmar, Cornils, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335698/
https://www.ncbi.nlm.nih.gov/pubmed/28256524
http://dx.doi.org/10.1038/srep43249