Cargando…

Nicotinic acid inhibits glioma invasion by facilitating Snail1 degradation

Malignant glioma is a formidable disease that commonly leads to death, mainly due to the invasion of tumor cells into neighboring tissues. Therefore, inhibition of tumor cell invasion may provide an effective therapy for malignant glioma. Here we report that nicotinic acid (NA), an essential vitamin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Jiejing, Qu, Jiagui, Shi, Yu, Perfetto, Mark, Ping, Zhuxian, Christian, Laura, Niu, Hua, Mei, Shuting, Zhang, Qin, Yang, Xiangcai, Wei, Shuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335718/ https://www.ncbi.nlm.nih.gov/pubmed/28256591 http://dx.doi.org/10.1038/srep43173

Ejemplares similares

Nicotinic acid impairs assembly of leading edge in glioma cells
por: Yang, Xiangcai, et al.
Publicado: (2017)

Acquisition of temozolomide resistance by the rat C6 glioma cell line increases cell migration and side population phenotype
por: Xu, Ya, et al.
Publicado: (2019)

Elongator Protein 3 (Elp3) stabilizes Snail1 and regulates neural crest migration in Xenopus
por: Yang, Xiangcai, et al.
Publicado: (2016)

Melatonin treatment increases the transcription of cell proliferation-related genes prior to inducing cell death in C6 glioma cells in vitro
por: QU, JIAGUI, et al.
Publicado: (2013)

Nicotinic acid modulates intracellular calcium concentration and disassembles the cytoskeleton
por: LI, JIEJING, et al.
Publicado: (2014)

GTSE1 promotes SNAIL1 degradation by facilitating its nuclear export in hepatocellular carcin oma cells
por: Li, Shan-Shan, et al.
Publicado: (2021)

Neuronal Nicotinic Acetylcholine Receptor Modulators from Cone Snails
por: Abraham, Nikita, et al.
Publicado: (2018)

LKB1 suppresses glioma cell invasion via NF-κB/Snail signaling repression
por: Yuan, Ye, et al.
Publicado: (2019)

Invasive Fresh Water Snail, China
por: Wang, Qiao-Ping, et al.
Publicado: (2007)

SIRT2 promotes the viability, invasion and metastasis of osteosarcoma cells by inhibiting the degradation of Snail
por: Tian, Yonghao, et al.
Publicado: (2022)

Identification of Molecular Pathways Facilitating Glioma Cell Invasion In Situ
por: Nevo, Ido, et al.
Publicado: (2014)

Bacillus sp. YC7 from intestines of Lasioderma serricorne degrades nicotine due to nicotine dehydrogenase
por: Zhang, Ke, et al.
Publicado: (2023)

Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation
por: Wu, Yadi, et al.
Publicado: (2017)

RND3 promotes Snail 1 protein degradation and inhibits glioblastoma cell migration and invasion
por: Liu, Baohui, et al.
Publicado: (2016)

Regulatory Mechanism of Nicotine Degradation in Pseudomonas putida
por: Hu, Haiyang, et al.
Publicado: (2019)

CRNDE/ETS1/GPR17 Facilitates the Proliferation, Migration, and Invasion of Glioma
por: Hu, Yan, et al.
Publicado: (2021)

Emodin inhibits invasion and migration of hepatocellular carcinoma cells via regulating autophagy-mediated degradation of snail and β-catenin
por: Qin, Binyu, et al.
Publicado: (2022)

Effect of long-term temperature stress on the intestinal microbiome of an invasive snail
por: Li, Shuxian, et al.
Publicado: (2022)

Systematic Unraveling of the Unsolved Pathway of Nicotine Degradation in Pseudomonas
por: Tang, Hongzhi, et al.
Publicado: (2013)

Nodal Promotes the Migration and Invasion of Bladder Cancer Cells via Regulation of Snail
por: Chen, Wenwei, et al.
Publicado: (2019)

The PSMD14 inhibitor Thiolutin as a novel therapeutic approach for esophageal squamous cell carcinoma through facilitating SNAIL degradation
por: Jing, Chao, et al.
Publicado: (2021)

TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1
por: Li, Rongkun, et al.
Publicado: (2021)

Downregulated F-Box/LRR-Repeat Protein 7 Facilitates Pancreatic Cancer Metastasis by Regulating Snail1 for Proteasomal Degradation
por: Tang, Liang, et al.
Publicado: (2021)

DDR2 facilitates hepatocellular carcinoma invasion and metastasis via activating ERK signaling and stabilizing SNAIL1
por: Xie, Binhui, et al.
Publicado: (2015)

Kiaa0101 serves as a prognostic marker and promotes invasion by regulating p38/snail1 pathway in glioma
por: Liu, Junhui, et al.
Publicado: (2021)

Optimization of a nicotine degrading enzyme for potential use in treatment of nicotine addiction
por: Thisted, Thomas, et al.
Publicado: (2019)

The nicotine-degrading enzyme NicA2 reduces nicotine levels in blood, nicotine distribution to brain, and nicotine discrimination and reinforcement in rats
por: Pentel, Paul R., et al.
Publicado: (2018)

Notch1 binds and induces degradation of Snail in hepatocellular carcinoma
por: Lim, Seung-Oe, et al.
Publicado: (2011)

Nodal Promotes the Migration and Invasion of Bladder Cancer Cells via Regulation of Snail: Erratum
por: Chen, Wenwei, et al.
Publicado: (2022)

Structural, Mechanistic, and Functional Insights into an Arthrobacter nicotinovorans Molybdenum Hydroxylase Involved in Nicotine Degradation
por: Wang, Lei, et al.
Publicado: (2021)

A new transgenic reporter line reveals Wnt-dependent Snai2 re-expression and cranial neural crest differentiation in Xenopus
por: Li, Jiejing, et al.
Publicado: (2019)

Snail promotes an invasive phenotype in lung carcinoma
por: Merikallio, Heta, et al.
Publicado: (2012)

SMC1A facilitates gastric cancer cell proliferation, migration, and invasion via promoting SNAIL activated EMT
por: Liu, Yaling, et al.
Publicado: (2023)

14‐3‐3ζ promotes gliomas cells invasion by regulating Snail through the PI3K/AKT signaling
por: Li, Junjun, et al.
Publicado: (2019)

Overexpression of FBXO17 Promotes the Proliferation, Migration and Invasion of Glioma Cells Through the Akt/GSK-3β/Snail Pathway
por: Wang, Ning, et al.
Publicado: (2021)

Degradation Kinetics of Benzyl Nicotinate in Aqueous Solution
por: Mbah, C. J.
Publicado: (2010)

The potential risk of Schistosoma mansoni transmission by the invasive freshwater snail Biomphalaria straminea in South China
por: Lin, DaTao, et al.
Publicado: (2020)

NXN suppresses metastasis of hepatocellular carcinoma by promoting degradation of Snail through binding to DUB3
por: Zhang, Yuanping, et al.
Publicado: (2022)

TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation
por: Ma, Xiaoxiao, et al.
Publicado: (2018)

FOXM1 Promotes Lung Adenocarcinoma Invasion and Metastasis by Upregulating SNAIL
por: Wei, Ping, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_16unehrqg2a2bv5rp2gt173j7c