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The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activator dh404 protects against diabetes-induced endothelial dysfunction
BACKGROUND: Vascular dysfunction is a pivotal event in the development of diabetes-associated vascular disease. Increased inflammation and oxidative stress are major contributors to vascular dysfunction. Nrf2, a master regulator of several anti-oxidant genes and a suppressor of inflammatory NF-κB, h...
Autores principales: | Sharma, Arpeeta, Rizky, Luddwi, Stefanovic, Nada, Tate, Mitchel, Ritchie, Rebecca H., Ward, Keith W., de Haan, Judy B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335831/ https://www.ncbi.nlm.nih.gov/pubmed/28253885 http://dx.doi.org/10.1186/s12933-017-0513-y |
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