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A Versatile and Reproducible Multi-Frequency Electrical Impedance Tomography System

A highly versatile Electrical Impedance Tomography (EIT) system, nicknamed the ScouseTom, has been developed. The system allows control over current amplitude, frequency, number of electrodes, injection protocol and data processing. Current is injected using a Keithley 6221 current source, and volta...

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Detalles Bibliográficos
Autores principales: Avery, James, Dowrick, Thomas, Faulkner, Mayo, Goren, Nir, Holder, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336119/
https://www.ncbi.nlm.nih.gov/pubmed/28146122
http://dx.doi.org/10.3390/s17020280
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author Avery, James
Dowrick, Thomas
Faulkner, Mayo
Goren, Nir
Holder, David
author_facet Avery, James
Dowrick, Thomas
Faulkner, Mayo
Goren, Nir
Holder, David
author_sort Avery, James
collection PubMed
description A highly versatile Electrical Impedance Tomography (EIT) system, nicknamed the ScouseTom, has been developed. The system allows control over current amplitude, frequency, number of electrodes, injection protocol and data processing. Current is injected using a Keithley 6221 current source, and voltages are recorded with a 24-bit EEG system with minimum bandwidth of 3.2 kHz. Custom PCBs interface with a PC to control the measurement process, electrode addressing and triggering of external stimuli. The performance of the system was characterised using resistor phantoms to represent human scalp recordings, with an SNR of 77.5 dB, stable across a four hour recording and 20 Hz to 20 kHz. In studies of both haeomorrhage using scalp electrodes, and evoked activity using epicortical electrode mats in rats, it was possible to reconstruct images matching established literature at known areas of onset. Data collected using scalp electrode in humans matched known tissue impedance spectra and was stable over frequency. The experimental procedure is software controlled and is readily adaptable to new paradigms. Where possible, commercial or open-source components were used, to minimise the complexity in reproduction. The hardware designs and software for the system have been released under an open source licence, encouraging contributions and allowing for rapid replication.
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spelling pubmed-53361192017-03-16 A Versatile and Reproducible Multi-Frequency Electrical Impedance Tomography System Avery, James Dowrick, Thomas Faulkner, Mayo Goren, Nir Holder, David Sensors (Basel) Article A highly versatile Electrical Impedance Tomography (EIT) system, nicknamed the ScouseTom, has been developed. The system allows control over current amplitude, frequency, number of electrodes, injection protocol and data processing. Current is injected using a Keithley 6221 current source, and voltages are recorded with a 24-bit EEG system with minimum bandwidth of 3.2 kHz. Custom PCBs interface with a PC to control the measurement process, electrode addressing and triggering of external stimuli. The performance of the system was characterised using resistor phantoms to represent human scalp recordings, with an SNR of 77.5 dB, stable across a four hour recording and 20 Hz to 20 kHz. In studies of both haeomorrhage using scalp electrodes, and evoked activity using epicortical electrode mats in rats, it was possible to reconstruct images matching established literature at known areas of onset. Data collected using scalp electrode in humans matched known tissue impedance spectra and was stable over frequency. The experimental procedure is software controlled and is readily adaptable to new paradigms. Where possible, commercial or open-source components were used, to minimise the complexity in reproduction. The hardware designs and software for the system have been released under an open source licence, encouraging contributions and allowing for rapid replication. MDPI 2017-01-31 /pmc/articles/PMC5336119/ /pubmed/28146122 http://dx.doi.org/10.3390/s17020280 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Avery, James
Dowrick, Thomas
Faulkner, Mayo
Goren, Nir
Holder, David
A Versatile and Reproducible Multi-Frequency Electrical Impedance Tomography System
title A Versatile and Reproducible Multi-Frequency Electrical Impedance Tomography System
title_full A Versatile and Reproducible Multi-Frequency Electrical Impedance Tomography System
title_fullStr A Versatile and Reproducible Multi-Frequency Electrical Impedance Tomography System
title_full_unstemmed A Versatile and Reproducible Multi-Frequency Electrical Impedance Tomography System
title_short A Versatile and Reproducible Multi-Frequency Electrical Impedance Tomography System
title_sort versatile and reproducible multi-frequency electrical impedance tomography system
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336119/
https://www.ncbi.nlm.nih.gov/pubmed/28146122
http://dx.doi.org/10.3390/s17020280
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