Cargando…
A Versatile and Reproducible Multi-Frequency Electrical Impedance Tomography System
A highly versatile Electrical Impedance Tomography (EIT) system, nicknamed the ScouseTom, has been developed. The system allows control over current amplitude, frequency, number of electrodes, injection protocol and data processing. Current is injected using a Keithley 6221 current source, and volta...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336119/ https://www.ncbi.nlm.nih.gov/pubmed/28146122 http://dx.doi.org/10.3390/s17020280 |
_version_ | 1782512165960286208 |
---|---|
author | Avery, James Dowrick, Thomas Faulkner, Mayo Goren, Nir Holder, David |
author_facet | Avery, James Dowrick, Thomas Faulkner, Mayo Goren, Nir Holder, David |
author_sort | Avery, James |
collection | PubMed |
description | A highly versatile Electrical Impedance Tomography (EIT) system, nicknamed the ScouseTom, has been developed. The system allows control over current amplitude, frequency, number of electrodes, injection protocol and data processing. Current is injected using a Keithley 6221 current source, and voltages are recorded with a 24-bit EEG system with minimum bandwidth of 3.2 kHz. Custom PCBs interface with a PC to control the measurement process, electrode addressing and triggering of external stimuli. The performance of the system was characterised using resistor phantoms to represent human scalp recordings, with an SNR of 77.5 dB, stable across a four hour recording and 20 Hz to 20 kHz. In studies of both haeomorrhage using scalp electrodes, and evoked activity using epicortical electrode mats in rats, it was possible to reconstruct images matching established literature at known areas of onset. Data collected using scalp electrode in humans matched known tissue impedance spectra and was stable over frequency. The experimental procedure is software controlled and is readily adaptable to new paradigms. Where possible, commercial or open-source components were used, to minimise the complexity in reproduction. The hardware designs and software for the system have been released under an open source licence, encouraging contributions and allowing for rapid replication. |
format | Online Article Text |
id | pubmed-5336119 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-53361192017-03-16 A Versatile and Reproducible Multi-Frequency Electrical Impedance Tomography System Avery, James Dowrick, Thomas Faulkner, Mayo Goren, Nir Holder, David Sensors (Basel) Article A highly versatile Electrical Impedance Tomography (EIT) system, nicknamed the ScouseTom, has been developed. The system allows control over current amplitude, frequency, number of electrodes, injection protocol and data processing. Current is injected using a Keithley 6221 current source, and voltages are recorded with a 24-bit EEG system with minimum bandwidth of 3.2 kHz. Custom PCBs interface with a PC to control the measurement process, electrode addressing and triggering of external stimuli. The performance of the system was characterised using resistor phantoms to represent human scalp recordings, with an SNR of 77.5 dB, stable across a four hour recording and 20 Hz to 20 kHz. In studies of both haeomorrhage using scalp electrodes, and evoked activity using epicortical electrode mats in rats, it was possible to reconstruct images matching established literature at known areas of onset. Data collected using scalp electrode in humans matched known tissue impedance spectra and was stable over frequency. The experimental procedure is software controlled and is readily adaptable to new paradigms. Where possible, commercial or open-source components were used, to minimise the complexity in reproduction. The hardware designs and software for the system have been released under an open source licence, encouraging contributions and allowing for rapid replication. MDPI 2017-01-31 /pmc/articles/PMC5336119/ /pubmed/28146122 http://dx.doi.org/10.3390/s17020280 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Avery, James Dowrick, Thomas Faulkner, Mayo Goren, Nir Holder, David A Versatile and Reproducible Multi-Frequency Electrical Impedance Tomography System |
title | A Versatile and Reproducible Multi-Frequency Electrical Impedance Tomography System |
title_full | A Versatile and Reproducible Multi-Frequency Electrical Impedance Tomography System |
title_fullStr | A Versatile and Reproducible Multi-Frequency Electrical Impedance Tomography System |
title_full_unstemmed | A Versatile and Reproducible Multi-Frequency Electrical Impedance Tomography System |
title_short | A Versatile and Reproducible Multi-Frequency Electrical Impedance Tomography System |
title_sort | versatile and reproducible multi-frequency electrical impedance tomography system |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336119/ https://www.ncbi.nlm.nih.gov/pubmed/28146122 http://dx.doi.org/10.3390/s17020280 |
work_keys_str_mv | AT averyjames aversatileandreproduciblemultifrequencyelectricalimpedancetomographysystem AT dowrickthomas aversatileandreproduciblemultifrequencyelectricalimpedancetomographysystem AT faulknermayo aversatileandreproduciblemultifrequencyelectricalimpedancetomographysystem AT gorennir aversatileandreproduciblemultifrequencyelectricalimpedancetomographysystem AT holderdavid aversatileandreproduciblemultifrequencyelectricalimpedancetomographysystem AT averyjames versatileandreproduciblemultifrequencyelectricalimpedancetomographysystem AT dowrickthomas versatileandreproduciblemultifrequencyelectricalimpedancetomographysystem AT faulknermayo versatileandreproduciblemultifrequencyelectricalimpedancetomographysystem AT gorennir versatileandreproduciblemultifrequencyelectricalimpedancetomographysystem AT holderdavid versatileandreproduciblemultifrequencyelectricalimpedancetomographysystem |