Differential depletion of total T cells and regulatory T cells and prolonged allotransplant survival in CD3Ɛ humanized mice treated with polyclonal anti human thymocyte globulin

Thymoglobulin (ATG) is a polyclonal rabbit antibody against human thymocytes used as a T cell-depleting agent to prevent or treat allotransplant rejection. The aim of the present study was to investigate the effect of low dose ATG treatment exclusively on T cells using a humanized BALB/c human CD3Ɛ...

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Detalles Bibliográficos
Autores principales: Buszko, Maja, Cardini, Benno, Oberhuber, Rupert, Oberhuber, Lukas, Jakic, Bojana, Beierfuss, Anja, Wick, Georg, Cappellano, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336254/
https://www.ncbi.nlm.nih.gov/pubmed/28257450
http://dx.doi.org/10.1371/journal.pone.0173088

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