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Exposure to sequestered self-antigens in vivo is not sufficient for the induction of autoimmune diabetes
Although the role of T cells in autoimmunity has been explored for many years, the mechanisms leading to the initial priming of an autoimmune T cell response remain enigmatic. The ‘hit and run’ model suggests that self-antigens released upon cell death can provide the initial signal for a self-susta...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336264/ https://www.ncbi.nlm.nih.gov/pubmed/28257518 http://dx.doi.org/10.1371/journal.pone.0173176 |