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Nucleotide pools dictate the identity and frequency of ribonucleotide incorporation in mitochondrial DNA

Previous work has demonstrated the presence of ribonucleotides in human mitochondrial DNA (mtDNA) and in the present study we use a genome-wide approach to precisely map the location of these. We find that ribonucleotides are distributed evenly between the heavy- and light-strand of mtDNA. The relat...

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Detalles Bibliográficos
Autores principales:	Berglund, Anna-Karin, Navarrete, Clara, Engqvist, Martin K. M., Hoberg, Emily, Szilagyi, Zsolt, Taylor, Robert W., Gustafsson, Claes M., Falkenberg, Maria, Clausen, Anders R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336301/ https://www.ncbi.nlm.nih.gov/pubmed/28207748 http://dx.doi.org/10.1371/journal.pgen.1006628

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