Cargando…

JMJD-5/KDM8 regulates H3K36me2 and is required for late steps of homologous recombination and genome integrity

The eukaryotic genome is organized in a three-dimensional structure called chromatin, constituted by DNA and associated proteins, the majority of which are histones. Post-translational modifications of histone proteins greatly influence chromatin structure and regulate many DNA-based biological proc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Amendola, Pier Giorgio, Zaghet, Nico, Ramalho, João J., Vilstrup Johansen, Jens, Boxem, Mike, Salcini, Anna Elisabetta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336306/ https://www.ncbi.nlm.nih.gov/pubmed/28207814 http://dx.doi.org/10.1371/journal.pgen.1006632

Ejemplares similares

Coordinated maintenance of H3K36/K27 methylation by histone demethylases preserves germ cell identity and immortality
por: Zaghet, Nico, et al.
Publicado: (2021)

JMJD-1.2 controls multiple histone post-translational modifications in germ cells and protects the genome from replication stress
por: Myers, Toshia R., et al.
Publicado: (2018)

Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells
por: Agger, Karl, et al.
Publicado: (2016)

The Histone Lysine Demethylase JMJD3/KDM6B Is Recruited to p53 Bound Promoters and Enhancer Elements in a p53 Dependent Manner
por: Williams, Kristine, et al.
Publicado: (2014)

SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade
por: Romero, Octavio A., et al.
Publicado: (2021)

The C. elegans Crumbs family contains a CRB3 homolog and is not essential for viability
por: Waaijers, Selma, et al.
Publicado: (2015)

Regulation of the JMJD3 (KDM6B) histone demethylase in glioblastoma stem cells by STAT3
por: Sherry-Lynes, Maureen M., et al.
Publicado: (2017)

KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes
por: Sankar, Aditya, et al.
Publicado: (2020)

A New Isoform of the Histone Demethylase JMJD2A/KDM4A Is Required for Skeletal Muscle Differentiation
por: Verrier, Laure, et al.
Publicado: (2011)

The histone demethylase JMJD2A/KDM4A links ribosomal RNA transcription to nutrients and growth factors availability
por: Salifou, Kader, et al.
Publicado: (2016)

Heme promotes transcriptional and demethylase activities of Gis1, a member of the histone demethylase JMJD2/KDM4 family
por: Lal, Sneha, et al.
Publicado: (2018)

Control of enhancer and promoter activation in the type I interferon response by the histone demethylase Kdm4d/JMJD2d
por: Chandwani, Rohit, et al.
Publicado: (2023)

The Eps15 Homology (Eh) Domain-Based Interaction between Eps15 and Hrb Connects the Molecular Machinery of Endocytosis to That of Nucleocytosolic Transport
por: Doria, Margherita, et al.
Publicado: (1999)

Regulation of Tumor Suppressor p53 and HCT116 Cell Physiology by Histone Demethylase JMJD2D/KDM4D
por: Kim, Tae-Dong, et al.
Publicado: (2012)

Therapeutic potential of GSK-J4, a histone demethylase KDM6B/JMJD3 inhibitor, for acute myeloid leukemia
por: Li, Yunan, et al.
Publicado: (2018)

Epigenetic regulation of TGF-β-induced EMT by JMJD3/KDM6B histone H3K27 demethylase
por: Lee, Su-Hyun, et al.
Publicado: (2021)

KDM4B-mediated reduction of H3K9me3 and H3K36me3 levels improves somatic cell reprogramming into pluripotency
por: Wei, Jingwei, et al.
Publicado: (2017)

KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC
por: Wang, Hung-Jung, et al.
Publicado: (2018)

8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors
por: Bavetsias, Vassilios, et al.
Publicado: (2016)

The Novel Protease Activities of JMJD5–JMJD6–JMJD7 and Arginine Methylation Activities of Arginine Methyltransferases Are Likely Coupled
por: Liu, Haolin, et al.
Publicado: (2022)

Histone H3K36me2 demethylase KDM2A promotes bladder cancer progression through epigenetically silencing RARRES3
por: Lu, Bing, et al.
Publicado: (2022)

KDM4B/JMJD2B is a p53 target gene that modulates the amplitude of p53 response after DNA damage
por: Castellini, Laura, et al.
Publicado: (2017)

IL-13 Augments Histone Demethylase JMJD2B/KDM4B Expression Levels, Activity, and Nuclear Translocation in Airway Fibroblasts in Asthma
por: Bajbouj, Khuloud, et al.
Publicado: (2021)

Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7
por: Liu, Haolin, et al.
Publicado: (2018)

HP1a Targets the Drosophila KDM4A Demethylase to a Subset of Heterochromatic Genes to Regulate H3K36me3 Levels
por: Lin, Chia-Hui, et al.
Publicado: (2012)

Histone H3K9 demethylase JMJD2B/KDM4B promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells by regulating H3K9me2 on RUNX2
por: Kang, Pan, et al.
Publicado: (2022)

BRCC36A is epistatic to BRCA1 in DNA crosslink repair and homologous recombination in Arabidopsis thaliana
por: Block-Schmidt, Astrid S., et al.
Publicado: (2011)

Kdm2a deficiency in macrophages enhances thermogenesis to protect mice against HFD-induced obesity by enhancing H3K36me2 at the Pparg locus
por: Chen, Longmin, et al.
Publicado: (2021)

Tumor homologous recombination deficiency assays: another step closer to clinical application?
por: Stecklein, Shane R, et al.
Publicado: (2014)

Identification of the histone lysine demethylase KDM4A/JMJD2A as a novel epigenetic target in M1 macrophage polarization induced by oxidized LDL
por: Wang, Xue, et al.
Publicado: (2017)

Histone demethylase JMJD2B/KDM4B regulates transcriptional program via distinctive epigenetic targets and protein interactors for the maintenance of trophoblast stem cells
por: Mak, Kylie Hin-Man, et al.
Publicado: (2021)

A Snapshot of the Physical and Functional Wiring of the Eps15 Homology Domain Network in the Nematode
por: Tsushima, Hanako, et al.
Publicado: (2013)

SIRT6 mono-ADP ribosylates KDM2A to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair
por: Rezazadeh, Sarallah, et al.
Publicado: (2020)

JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes
por: Lee, Schuyler, et al.
Publicado: (2020)

Histone Lysine Demethylase JMJD2D/KDM4D and Family Members Mediate Effects of Chronic Social Defeat Stress on Mouse Hippocampal Neurogenesis and Mood Disorders
por: Maitra, Swati, et al.
Publicado: (2020)

H3K23me2 is a new heterochromatic mark in Caenorhabditis elegans
por: Vandamme, Julien, et al.
Publicado: (2015)

Vitamin C induces specific demethylation of H3K9me2 in mouse embryonic stem cells via Kdm3a/b
por: Ebata, Kevin T., et al.
Publicado: (2017)

Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination
por: Onyango, David O., et al.
Publicado: (2016)

Role of JMJD6 in Breast Tumourigenesis
por: Poulard, Coralie, et al.
Publicado: (2015)

JMJD3 in the regulation of human diseases
por: Zhang, Xiangxian, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_tcvh2j02lq7baiarbd8kk5hcdq