Transcriptional signatures of unfolded protein response implicate the limitation of animal models in pathophysiological studies

BACKGROUND: The unfolded protein response (UPR) refers to intracellular stress signaling pathways that protect cells from the stress caused by accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER). The UPR signaling is crucially involved in the initiation and progression o...

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Detalles Bibliográficos
Autores principales: Zheng, Ze, Wang, Guohui, Li, Li, Tseng, Jeffery, Sun, Fei, Chen, Xuequn, Chang, Lin, Heng, Henry, Zhang, Kezhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336312/
https://www.ncbi.nlm.nih.gov/pubmed/28265594

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