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A Report of Two Cases of Solid Facial Edema in Acne
INTRODUCTION: Solid facial edema (SFE) is a rare complication of acne vulgaris. To examine the clinical features of acne patients with solid facial edema, and to give an overview on the outcome of previous topical and systemic treatments in the cases so far published. METHODS: We report two cases fr...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Healthcare
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336436/ https://www.ncbi.nlm.nih.gov/pubmed/28168623 http://dx.doi.org/10.1007/s13555-017-0173-6 |
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author | Kuhn-Régnier, Sarah Mangana, Joanna Kerl, Katrin Kamarachev, Jivko French, Lars E. Cozzio, Antonio Navarini, Alexander A. |
author_facet | Kuhn-Régnier, Sarah Mangana, Joanna Kerl, Katrin Kamarachev, Jivko French, Lars E. Cozzio, Antonio Navarini, Alexander A. |
author_sort | Kuhn-Régnier, Sarah |
collection | PubMed |
description | INTRODUCTION: Solid facial edema (SFE) is a rare complication of acne vulgaris. To examine the clinical features of acne patients with solid facial edema, and to give an overview on the outcome of previous topical and systemic treatments in the cases so far published. METHODS: We report two cases from Switzerland, both young men with initially papulopustular acne resistant to topical retinoids. RESULTS: Both cases responded to oral isotretinoin, in one case combined with oral steroids. Our cases show a strikingly similar clinical appearance to the cases described by Connelly and Winkelmann in 1985 (Connelly MG, Winkelmann RK. Solid facial edema as a complication of acne vulgaris. Arch Dermatol. 1985;121(1):87), as well as to cases of Morbihan’s disease that occurs as a rare complication of rosacea. CONCLUSION: Even 30 years after, the cause of the edema remains unknown. In two of the original four cases, a potential triggering factor was identified such as facial trauma or insect bites; however, our two patients did not report such occurrencies. The rare cases of solid facial edema in both acne and rosacea might hold the key to understanding the specific inflammatory pattern that creates both persisting inflammation and disturbed fluid homeostasis which can occur as a slightly different presentation in dermatomyositis, angioedema, Heerfordt’s syndrome and other conditions. |
format | Online Article Text |
id | pubmed-5336436 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Springer Healthcare |
record_format | MEDLINE/PubMed |
spelling | pubmed-53364362017-03-16 A Report of Two Cases of Solid Facial Edema in Acne Kuhn-Régnier, Sarah Mangana, Joanna Kerl, Katrin Kamarachev, Jivko French, Lars E. Cozzio, Antonio Navarini, Alexander A. Dermatol Ther (Heidelb) Case Report INTRODUCTION: Solid facial edema (SFE) is a rare complication of acne vulgaris. To examine the clinical features of acne patients with solid facial edema, and to give an overview on the outcome of previous topical and systemic treatments in the cases so far published. METHODS: We report two cases from Switzerland, both young men with initially papulopustular acne resistant to topical retinoids. RESULTS: Both cases responded to oral isotretinoin, in one case combined with oral steroids. Our cases show a strikingly similar clinical appearance to the cases described by Connelly and Winkelmann in 1985 (Connelly MG, Winkelmann RK. Solid facial edema as a complication of acne vulgaris. Arch Dermatol. 1985;121(1):87), as well as to cases of Morbihan’s disease that occurs as a rare complication of rosacea. CONCLUSION: Even 30 years after, the cause of the edema remains unknown. In two of the original four cases, a potential triggering factor was identified such as facial trauma or insect bites; however, our two patients did not report such occurrencies. The rare cases of solid facial edema in both acne and rosacea might hold the key to understanding the specific inflammatory pattern that creates both persisting inflammation and disturbed fluid homeostasis which can occur as a slightly different presentation in dermatomyositis, angioedema, Heerfordt’s syndrome and other conditions. Springer Healthcare 2017-02-06 /pmc/articles/PMC5336436/ /pubmed/28168623 http://dx.doi.org/10.1007/s13555-017-0173-6 Text en © The Author(s) 2017 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Case Report Kuhn-Régnier, Sarah Mangana, Joanna Kerl, Katrin Kamarachev, Jivko French, Lars E. Cozzio, Antonio Navarini, Alexander A. A Report of Two Cases of Solid Facial Edema in Acne |
title | A Report of Two Cases of Solid Facial Edema in Acne |
title_full | A Report of Two Cases of Solid Facial Edema in Acne |
title_fullStr | A Report of Two Cases of Solid Facial Edema in Acne |
title_full_unstemmed | A Report of Two Cases of Solid Facial Edema in Acne |
title_short | A Report of Two Cases of Solid Facial Edema in Acne |
title_sort | report of two cases of solid facial edema in acne |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336436/ https://www.ncbi.nlm.nih.gov/pubmed/28168623 http://dx.doi.org/10.1007/s13555-017-0173-6 |
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