In Vitro and In Vivo Modeling of Hydroxypropyl Methylcellulose (HPMC) Matrix Tablet Erosion Under Fasting and Postprandial Status

PURPOSE: To develop a model linking in vitro and in vivo erosion of extended release tablets under fasting and postprandial status. METHODS: A nonlinear mixed-effects model was developed from the in vitro erosion profiles of four hydroxypropyl methylcellulose (HPMC) matrix tablets studied under a ra...

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Detalles Bibliográficos
Autores principales: Guiastrennec, Benjamin, Söderlind, Erik, Richardson, Sara, Peric, Alexandra, Bergstrand, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336534/
https://www.ncbi.nlm.nih.gov/pubmed/28155077
http://dx.doi.org/10.1007/s11095-017-2113-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336534/
https://www.ncbi.nlm.nih.gov/pubmed/28155077
http://dx.doi.org/10.1007/s11095-017-2113-7

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