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A Giant Brunneroma Causing Gastrointestinal Bleeding and Severe Anemia Requiring Transfusion and Surgery

Brunner's gland hamartoma, also called hyperplasia, adenoma, and Brunneroma, is an extremely rare benign proliferative lesion of Brunner's glands in the duodenum. While being mostly small and asymptomatic, they can result in gastrointestinal bleeding and obstruction. We report the case of...

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Autores principales: Frenkel, Nicola C., Laclé, Miangela M., Borel Rinkes, Inne H. M., Molenaar, Izaak Q., Hagendoorn, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337360/
https://www.ncbi.nlm.nih.gov/pubmed/28299229
http://dx.doi.org/10.1155/2017/6940649
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author Frenkel, Nicola C.
Laclé, Miangela M.
Borel Rinkes, Inne H. M.
Molenaar, Izaak Q.
Hagendoorn, Jeroen
author_facet Frenkel, Nicola C.
Laclé, Miangela M.
Borel Rinkes, Inne H. M.
Molenaar, Izaak Q.
Hagendoorn, Jeroen
author_sort Frenkel, Nicola C.
collection PubMed
description Brunner's gland hamartoma, also called hyperplasia, adenoma, and Brunneroma, is an extremely rare benign proliferative lesion of Brunner's glands in the duodenum. While being mostly small and asymptomatic, they can result in gastrointestinal bleeding and obstruction. We report the case of a 54-year-old man presenting with melena and severe anemia requiring blood transfusion. CT scans showed a large mass of 8 cm in diameter, presumably arising in the duodenum. Endoscopic biopsies were not conclusive. As we were unable to determine the nature of the mass preoperatively and due to the severe symptoms, its size, and the uncertain malignant potential, a classic Whipple procedure was performed. The resected specimen showed extensive proliferation of Brunner's glands without signs of malignancy.
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spelling pubmed-53373602017-03-15 A Giant Brunneroma Causing Gastrointestinal Bleeding and Severe Anemia Requiring Transfusion and Surgery Frenkel, Nicola C. Laclé, Miangela M. Borel Rinkes, Inne H. M. Molenaar, Izaak Q. Hagendoorn, Jeroen Case Rep Surg Case Report Brunner's gland hamartoma, also called hyperplasia, adenoma, and Brunneroma, is an extremely rare benign proliferative lesion of Brunner's glands in the duodenum. While being mostly small and asymptomatic, they can result in gastrointestinal bleeding and obstruction. We report the case of a 54-year-old man presenting with melena and severe anemia requiring blood transfusion. CT scans showed a large mass of 8 cm in diameter, presumably arising in the duodenum. Endoscopic biopsies were not conclusive. As we were unable to determine the nature of the mass preoperatively and due to the severe symptoms, its size, and the uncertain malignant potential, a classic Whipple procedure was performed. The resected specimen showed extensive proliferation of Brunner's glands without signs of malignancy. Hindawi Publishing Corporation 2017 2017-02-19 /pmc/articles/PMC5337360/ /pubmed/28299229 http://dx.doi.org/10.1155/2017/6940649 Text en Copyright © 2017 Nicola C. Frenkel et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Frenkel, Nicola C.
Laclé, Miangela M.
Borel Rinkes, Inne H. M.
Molenaar, Izaak Q.
Hagendoorn, Jeroen
A Giant Brunneroma Causing Gastrointestinal Bleeding and Severe Anemia Requiring Transfusion and Surgery
title A Giant Brunneroma Causing Gastrointestinal Bleeding and Severe Anemia Requiring Transfusion and Surgery
title_full A Giant Brunneroma Causing Gastrointestinal Bleeding and Severe Anemia Requiring Transfusion and Surgery
title_fullStr A Giant Brunneroma Causing Gastrointestinal Bleeding and Severe Anemia Requiring Transfusion and Surgery
title_full_unstemmed A Giant Brunneroma Causing Gastrointestinal Bleeding and Severe Anemia Requiring Transfusion and Surgery
title_short A Giant Brunneroma Causing Gastrointestinal Bleeding and Severe Anemia Requiring Transfusion and Surgery
title_sort giant brunneroma causing gastrointestinal bleeding and severe anemia requiring transfusion and surgery
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337360/
https://www.ncbi.nlm.nih.gov/pubmed/28299229
http://dx.doi.org/10.1155/2017/6940649
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