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Polymorphisms of IL12RB2 May Affect the Natural History of Primary Biliary Cholangitis: A Single Centre Study

Background. Recent GWAS in primary biliary cholangitis (PBC) showed strong associations with SNPs located within interleukin-12 receptor (IL12R) beta-2 (IL12RB2) gene. Aims. We assessed whether genetic variation of IL12RB2 is associated with laboratory and clinical features of PBC. Methods. Genomic...

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Detalles Bibliográficos
Autores principales: Wasik, Urszula, Wunsch, Ewa, Norman, Gary L., Rigopoulou, Eirini I., Bogdanos, Dimitrios P., Milkiewicz, Piotr, Milkiewicz, Małgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337364/
https://www.ncbi.nlm.nih.gov/pubmed/28299343
http://dx.doi.org/10.1155/2017/2185083

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