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Host FIH-Mediated Asparaginyl Hydroxylation of Translocated Legionella pneumophila Effectors

FIH-mediated post-translational modification through asparaginyl hydroxylation of eukaryotic proteins impacts regulation of protein-protein interaction. We have identified the FIH recognition motif in 11 Legionella pneumophila translocated effectors, YopM of Yersinia, IpaH4.5 of Shigella and an anky...

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Detalles Bibliográficos
Autores principales: Price, Christopher, Merchant, Michael, Jones, Snake, Best, Ashley, Von Dwingelo, Juanita, Lawrenz, Matthew B., Alam, Nawsad, Schueler-Furman, Ora, Kwaik, Yousef A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337513/
https://www.ncbi.nlm.nih.gov/pubmed/28321389
http://dx.doi.org/10.3389/fcimb.2017.00054