Cargando…

Heterogeneity of the Pancreatic Beta Cell

The pancreatic beta cell functions as a key regulator of blood glucose levels by integrating a variety of signals in response to changing metabolic demands. Variations in beta cell identity that translate into functionally different subpopulations represent an interesting mechanism to allow beta cel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gutierrez, Giselle Dominguez, Gromada, Jesper, Sussel, Lori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337801/ https://www.ncbi.nlm.nih.gov/pubmed/28321233 http://dx.doi.org/10.3389/fgene.2017.00022

Ejemplares similares

Heterogeneity of human pancreatic β-cells
por: Dominguez-Gutierrez, Giselle, et al.
Publicado: (2019)

mRNA Processing: An Emerging Frontier in the Regulation of Pancreatic β Cell Function
por: Moss, Nicole D., et al.
Publicado: (2020)

Long Non-coding RNAs as Local Regulators of Pancreatic Islet Transcription Factor Genes
por: Font-Cunill, Berta, et al.
Publicado: (2018)

Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development
por: Churchill, Angela J, et al.
Publicado: (2017)

Metabolic Stress and Compromised Identity of Pancreatic Beta Cells
por: Swisa, Avital, et al.
Publicado: (2017)

Single Molecule–Based fliFISH Validates Radial and Heterogeneous Gene Expression Patterns in Pancreatic Islet β-Cells
por: Li, Fangjia, et al.
Publicado: (2021)

Inherent Beta Cell Dysfunction Contributes to Autoimmune Susceptibility
por: Kim, Yong Kyung, et al.
Publicado: (2021)

Roles of lncRNAs in pancreatic beta cell identity and diabetes susceptibility
por: Pullen, Timothy J., et al.
Publicado: (2014)

Candidate gene association study suggests potential role of dopamine beta-hydroxylase in pain heterogeneity in sickle cell disease
por: Sadhu, Nilanjana, et al.
Publicado: (2023)

The Impact of Heterogeneity on Single-Cell Sequencing
por: Goldman, Samantha L., et al.
Publicado: (2019)

Analysis of Purified Pancreatic Islet Beta and Alpha Cell Transcriptomes Reveals 11β-Hydroxysteroid Dehydrogenase (Hsd11b1) as a Novel Disallowed Gene
por: Pullen, Timothy J., et al.
Publicado: (2017)

Beta 1, Beta 2 and Beta 3 Adrenergic Receptor Gene Polymorphisms in a Southeastern European Population
por: Katsarou, Martha-Spyridoula, et al.
Publicado: (2018)

Mitochondrial Heterogeneity
por: Aryaman, Juvid, et al.
Publicado: (2019)

The Impact of Pancreatic Beta Cell Heterogeneity on Type 1 Diabetes Pathogenesis
por: Benninger, Richard K. P., et al.
Publicado: (2018)

Single-cell RNA Sequencing Reveals Heterogeneity of Cultured Bovine Satellite Cells
por: Lyu, Pengcheng, et al.
Publicado: (2021)

Editorial: Beta-Cell Fate: From Gene Circuits to Disease Mechanisms
por: Ghila, Luiza, et al.
Publicado: (2022)

Concordant and Heterogeneity of Single-Cell Transcriptome in Cardiac Development of Human and Mouse
por: Shang, Mengyue, et al.
Publicado: (2022)

Gene Expression Noise Produces Cell-to-Cell Heterogeneity in Eukaryotic Homologous Recombination Rate
por: Liu, Jian, et al.
Publicado: (2019)

Leveraging the strengths of mice, human stem cells, and organoids to model pancreas development and diabetes
por: Lorberbaum, David S., et al.
Publicado: (2022)

Single-Cell RNA Sequencing-Based Computational Analysis to Describe Disease Heterogeneity
por: Zeng, Tao, et al.
Publicado: (2019)

Single-Cell RNA Sequencing Reveals Smooth Muscle Cells Heterogeneity in Experimental Aortic Dissection
por: Xu, Cheng, et al.
Publicado: (2022)

Heterogeneity in Metabolic Responses to Dietary Fructose
por: Hou, Ruixue, et al.
Publicado: (2019)

Spatial Transcriptomics for Tumor Heterogeneity Analysis
por: Li, Qiongyu, et al.
Publicado: (2022)

Genetic heterogeneity in corpus callosum agenesis
por: Pânzaru, Monica-Cristina, et al.
Publicado: (2022)

Characterisation of Ppy-lineage cells clarifies the functional heterogeneity of pancreatic beta cells in mice
por: Fukaishi, Takahiro, et al.
Publicado: (2021)

Unraveling Heterogeneity in Transcriptome and Its Regulation Through Single-Cell Multi-Omics Technologies
por: Xing, Qiao Rui, et al.
Publicado: (2020)

Single-Cell Transcriptomics Uncovers Cellular Heterogeneity, Mechanisms, and Therapeutic Targets for Parkinson’s Disease
por: Huang, Jianjun, et al.
Publicado: (2022)

Computational Methods for Characterizing Cancer Mutational Heterogeneity
por: Vandin, Fabio
Publicado: (2017)

Editorial: Non-Genetic Heterogeneity in Development and Disease
por: Capp, Jean-Pascal, et al.
Publicado: (2021)

Heterogeneity of Organization of Subcompartments in DSB Repair Foci
por: Abate, Natnael G., et al.
Publicado: (2022)

Editorial: Epigenomic polymorphisms: The drivers of diversity and heterogeneity
por: Dar, Tanvir-Ul-Hassan, et al.
Publicado: (2022)

Heterogeneous Skeletal Muscle Cell and Nucleus Populations Identified by Single-Cell and Single-Nucleus Resolution Transcriptome Assays
por: Williams, Katherine, et al.
Publicado: (2022)

Single-cell RNA sequencing analysis to explore immune cell heterogeneity and novel biomarkers for the prognosis of lung adenocarcinoma
por: Xu, Yong, et al.
Publicado: (2022)

Importance of Both Imprinted Genes and Functional Heterogeneity in Pancreatic Beta Cells: Is There a Link?
por: Chabosseau, Pauline, et al.
Publicado: (2021)

Heterogeneity of Genetic Admixture Determines SLE Susceptibility in Mexican
por: Hernández-Doño, Susana, et al.
Publicado: (2021)

The Missing lnc(RNA) between the pancreatic β-cell and diabetes
por: Kameswaran, Vasumathi, et al.
Publicado: (2014)

Missing Value Imputation With Low-Rank Matrix Completion in Single-Cell RNA-Seq Data by Considering Cell Heterogeneity
por: Huang, Meng, et al.
Publicado: (2022)

Differential Infiltration of Immune Cells Driven by Tumor Heterogeneity Reveals Two Immune Subtypes in Lung Adenocarcinoma
por: Wang, Liqiang, et al.
Publicado: (2022)

Islet Long Noncoding RNAs: A Playbook for Discovery and Characterization
por: Singer, Ruth A., et al.
Publicado: (2018)

Islet Regeneration: Endogenous and Exogenous Approaches
por: Docherty, Fiona M., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ibt0fh4vuktk64ol6qse29vtkc