PDGF‐induced fibroblast growth requires monounsaturated fatty acid production by stearoyl‐CoA desaturase

Stearoyl‐coenzyme A desaturase (SCD) catalyzes the Δ9‐cis desaturation of saturated fatty acids (SFA) to generate monounsaturated fatty acids (MUFA). This enzyme is highly up‐regulated by platelet‐derived growth factor (PDGF) in human fibroblasts. Accordingly, the analysis of cellular fatty acids by...

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Detalles Bibliográficos
Autores principales: Coomans de Brachène, Alexandra, Dif, Nicolas, de Rocca Serra, Audrey, Bonnineau, Chloé, Velghe, Amélie I., Larondelle, Yvan, Tyteca, Donatienne, Demoulin, Jean‐Baptiste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337901/
https://www.ncbi.nlm.nih.gov/pubmed/28286737
http://dx.doi.org/10.1002/2211-5463.12194

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