Alpha-1,3-galactosyltransferase-deficient miniature pigs produced by serial cloning using neonatal skin fibroblasts with loss of heterozygosity

OBJECTIVE: Production of alpha-1,3-galactosyltransferase (αGT)-deficient pigs is essential to overcome xenograft rejection in pig-to-human xenotransplantation. However, the production of such pigs requires a great deal of cost, time, and labor. Heterozygous αGT knockout pigs should be bred at least...

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Detalles Bibliográficos
Autores principales: Kim, Young June, Ahn, Kwang Sung, Kim, Minjeong, Kim, Min Ju, Ahn, Jin Seop, Ryu, Junghyun, Heo, Soon Young, Park, Sang-Min, Kang, Jee Hyun, Choi, You Jung, Shim, Hosup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian-Australasian Association of Animal Production Societies (AAAP) and Korean Society of Animal Science and Technology (KSAST) 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337925/
https://www.ncbi.nlm.nih.gov/pubmed/27165032
http://dx.doi.org/10.5713/ajas.16.0010

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