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Chronic alcohol consumption decreases brown adipose tissue mass and disrupts thermoregulation: a possible role for altered retinoid signaling

Retinoic acid, an active metabolite of dietary vitamin A, acts as a ligand for nuclear receptor transcription factors with more than 500 known target genes. It is becoming increasingly clear that alcohol has a significant impact on cellular retinoic acid metabolism, with resultant effects on its fun...

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Detalles Bibliográficos
Autores principales: Blaner, William S., Gao, Madeleine A., Jiang, Hongfeng, Dalmer, Timothy R. A., Hu, Xueyuan J., Ginsberg, Henry N., Clugston, Robin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337954/
https://www.ncbi.nlm.nih.gov/pubmed/28262768
http://dx.doi.org/10.1038/srep43474