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Chronic alcohol consumption decreases brown adipose tissue mass and disrupts thermoregulation: a possible role for altered retinoid signaling
Retinoic acid, an active metabolite of dietary vitamin A, acts as a ligand for nuclear receptor transcription factors with more than 500 known target genes. It is becoming increasingly clear that alcohol has a significant impact on cellular retinoic acid metabolism, with resultant effects on its fun...
Autores principales: | Blaner, William S., Gao, Madeleine A., Jiang, Hongfeng, Dalmer, Timothy R. A., Hu, Xueyuan J., Ginsberg, Henry N., Clugston, Robin D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337954/ https://www.ncbi.nlm.nih.gov/pubmed/28262768 http://dx.doi.org/10.1038/srep43474 |
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