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Functional annotation of sixty-five type-2 diabetes risk SNPs and its application in risk prediction
Genome-wide association studies (GWAS) have identified more than sixty single nucleotide polymorphisms (SNPs) associated with increased risk for type 2 diabetes (T2D). However, the identification of causal risk SNPs for T2D pathogenesis was complicated by the factor that each risk SNP is a surrogate...
Autores principales: | Wu, Yiming, Jing, Runyu, Dong, Yongcheng, Kuang, Qifan, Li, Yan, Huang, Ziyan, Gan, Wei, Xue, Yue, Li, Yizhou, Li, Menglong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337961/ https://www.ncbi.nlm.nih.gov/pubmed/28262806 http://dx.doi.org/10.1038/srep43709 |
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