Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression

Immune-mediated effector molecules can limit cancer growth, but lack of sustained immune activation in the tumour microenvironment restricts antitumour immunity. New therapeutic approaches that induce a strong and prolonged immune activation would represent a major immunotherapeutic advance. Here we...

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Detalles Bibliográficos
Autores principales: Kalkavan, Halime, Sharma, Piyush, Kasper, Stefan, Helfrich, Iris, Pandyra, Aleksandra A., Gassa, Asmae, Virchow, Isabel, Flatz, Lukas, Brandenburg, Tim, Namineni, Sukumar, Heikenwalder, Mathias, Höchst, Bastian, Knolle, Percy A., Wollmann, Guido, von Laer, Dorothee, Drexler, Ingo, Rathbun, Jessica, Cannon, Paula M., Scheu, Stefanie, Bauer, Jens, Chauhan, Jagat, Häussinger, Dieter, Willimsky, Gerald, Löhning, Max, Schadendorf, Dirk, Brandau, Sven, Schuler, Martin, Lang, Philipp A., Lang, Karl S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337983/
https://www.ncbi.nlm.nih.gov/pubmed/28248314
http://dx.doi.org/10.1038/ncomms14447

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