Cargando…

The influence of population stratification on genetic markers associated with type 1 diabetes

Ethnic admixtures may interfere with the definition of type 1 diabetes (T1D) risk determinants. The role of HLA, PTPN22, INS-VNTR, and CTLA4 in T1D predisposition was analyzed in Brazilian T1D patients (n = 915), with 81.7% self-reporting as white and 789 controls (65.6% white). The results were cor...

Descripción completa

Detalles Bibliográficos
Autores principales: Gomes, Karla Fabiana Brasil, Santos, Aritânia Sousa, Semzezem, Cintia, Correia, Márcia Regina, Brito, Luciano Abreu, Ruiz, Marcelo Ortega, Fukui, Rosa Tsuneshiro, Matioli, Sergio Russo, Passos-Bueno, Maria Rita, Silva, Maria Elizabeth Rossi da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338024/
https://www.ncbi.nlm.nih.gov/pubmed/28262800
http://dx.doi.org/10.1038/srep43513