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The influence of population stratification on genetic markers associated with type 1 diabetes
Ethnic admixtures may interfere with the definition of type 1 diabetes (T1D) risk determinants. The role of HLA, PTPN22, INS-VNTR, and CTLA4 in T1D predisposition was analyzed in Brazilian T1D patients (n = 915), with 81.7% self-reporting as white and 789 controls (65.6% white). The results were cor...
Autores principales: | Gomes, Karla Fabiana Brasil, Santos, Aritânia Sousa, Semzezem, Cintia, Correia, Márcia Regina, Brito, Luciano Abreu, Ruiz, Marcelo Ortega, Fukui, Rosa Tsuneshiro, Matioli, Sergio Russo, Passos-Bueno, Maria Rita, Silva, Maria Elizabeth Rossi da |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338024/ https://www.ncbi.nlm.nih.gov/pubmed/28262800 http://dx.doi.org/10.1038/srep43513 |
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