Cargo self-assembly rescues affinity of cell-penetrating peptides to lipid membranes

Although cationic cell-penetrating peptides (CPPs) are able to bind to cell membranes, thus promoting cell internalization by active pathways, attachment of cargo molecules to CPPs invariably reduces their cellular uptake. We show here that CPP binding to lipid bilayers, a simple model of the cell m...

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Detalles Bibliográficos
Autores principales: Weinberger, Andreas, Walter, Vivien, MacEwan, Sarah R., Schmatko, Tatiana, Muller, Pierre, Schroder, André P., Chilkoti, Ashutosh, Marques, Carlos M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338251/
https://www.ncbi.nlm.nih.gov/pubmed/28262825
http://dx.doi.org/10.1038/srep43963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338251/
https://www.ncbi.nlm.nih.gov/pubmed/28262825
http://dx.doi.org/10.1038/srep43963

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