Molecular Analysis of BRCA1 in Human Breast Cancer Cells Under Oxidative Stress

The precise manner in which physical changes to the breast cancer susceptibility protein (BRCA1) affect its role in DNA repair events remain unclear. Indeed, cancer cells harboring mutations in BRCA1 suffer from genomic instability and increased DNA lesions. Here, we used a combination of molecular...

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Detalles Bibliográficos
Autores principales: Gilmore, Brian L., Liang, Yanping, Winton, Carly E., Patel, Kaya, Karageorge, Vasilea, Varano, A. Cameron, Dearnaley, William, Sheng, Zhi, Kelly, Deborah F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338271/
https://www.ncbi.nlm.nih.gov/pubmed/28262780
http://dx.doi.org/10.1038/srep43435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338271/
https://www.ncbi.nlm.nih.gov/pubmed/28262780
http://dx.doi.org/10.1038/srep43435

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