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Single-Molecule Counting of Point Mutations by Transient DNA Binding

High-confidence detection of point mutations is important for disease diagnosis and clinical practice. Hybridization probes are extensively used, but are hindered by their poor single-nucleotide selectivity. Shortening the length of DNA hybridization probes weakens the stability of the probe-target...

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Detalles Bibliográficos
Autores principales:	Su, Xin, Li, Lidan, Wang, Shanshan, Hao, Dandan, Wang, Lei, Yu, Changyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338343/ https://www.ncbi.nlm.nih.gov/pubmed/28262827 http://dx.doi.org/10.1038/srep43824

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