A novel role for endothelial tetrahydrobiopterin in mitochondrial redox balance

The redox co-factor tetrahydrobiopterin (BH(4)) regulates nitric oxide (NO) and reactive oxygen species (ROS) production by endothelial NOS (eNOS) and is an important redox-dependent signalling molecule in the endothelium. Loss of endothelial BH(4) is observed in cardiovascular disease (CVD) states...

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Detalles Bibliográficos
Autores principales: Bailey, Jade, Shaw, Andrew, Fischer, Roman, Ryan, Brent J., Kessler, Benedikt M., McCullagh, James, Wade-Martins, Richard, Channon, Keith M., Crabtree, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338462/
https://www.ncbi.nlm.nih.gov/pubmed/28104455
http://dx.doi.org/10.1016/j.freeradbiomed.2017.01.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338462/
https://www.ncbi.nlm.nih.gov/pubmed/28104455
http://dx.doi.org/10.1016/j.freeradbiomed.2017.01.012

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