Role of tyrosine phosphorylation in sperm capacitation / acrosome reaction

Capacitation is an important physiological pre-requisite before the sperm cell can acrosome react and fertilize the oocyte. Recent reports from several laboratories have amply documented that the protein phosphorylation especially at tyrosine residues is one of the most important events that occur d...

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Detalles Bibliográficos
Autores principales: Naz, Rajesh K, Rajesh, Preeti B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC533862/
https://www.ncbi.nlm.nih.gov/pubmed/15535886
http://dx.doi.org/10.1186/1477-7827-2-75
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author Naz, Rajesh K
Rajesh, Preeti B
author_facet Naz, Rajesh K
Rajesh, Preeti B
author_sort Naz, Rajesh K
collection PubMed
description Capacitation is an important physiological pre-requisite before the sperm cell can acrosome react and fertilize the oocyte. Recent reports from several laboratories have amply documented that the protein phosphorylation especially at tyrosine residues is one of the most important events that occur during capacitation. In this article, we have reviewed the data from our and other laboratories, and have constructed a heuristic model for the mechanisms and molecules involved in capacitation/acrosome reaction.
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spelling pubmed-5338622004-11-26 Role of tyrosine phosphorylation in sperm capacitation / acrosome reaction Naz, Rajesh K Rajesh, Preeti B Reprod Biol Endocrinol Review Capacitation is an important physiological pre-requisite before the sperm cell can acrosome react and fertilize the oocyte. Recent reports from several laboratories have amply documented that the protein phosphorylation especially at tyrosine residues is one of the most important events that occur during capacitation. In this article, we have reviewed the data from our and other laboratories, and have constructed a heuristic model for the mechanisms and molecules involved in capacitation/acrosome reaction. BioMed Central 2004-11-09 /pmc/articles/PMC533862/ /pubmed/15535886 http://dx.doi.org/10.1186/1477-7827-2-75 Text en Copyright © 2004 Naz and Rajesh; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Naz, Rajesh K
Rajesh, Preeti B
Role of tyrosine phosphorylation in sperm capacitation / acrosome reaction
title Role of tyrosine phosphorylation in sperm capacitation / acrosome reaction
title_full Role of tyrosine phosphorylation in sperm capacitation / acrosome reaction
title_fullStr Role of tyrosine phosphorylation in sperm capacitation / acrosome reaction
title_full_unstemmed Role of tyrosine phosphorylation in sperm capacitation / acrosome reaction
title_short Role of tyrosine phosphorylation in sperm capacitation / acrosome reaction
title_sort role of tyrosine phosphorylation in sperm capacitation / acrosome reaction
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC533862/
https://www.ncbi.nlm.nih.gov/pubmed/15535886
http://dx.doi.org/10.1186/1477-7827-2-75
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