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Selective inhibition of c-Myb DNA-binding by RNA polymers

BACKGROUND: The transcription factor c-Myb is expressed in hematopoietic progenitor cells and other rapidly proliferating tissues, regulating genes important for proliferation, differentiation and survival. The DNA-binding domain (DBD) of c-Myb contains three tandemly arranged imperfect repeats, des...

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Detalles Bibliográficos
Autores principales: Nordgård, Oddmund, Andersen, Tor Ø, Gabrielsen, Odd S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC533864/
https://www.ncbi.nlm.nih.gov/pubmed/15527501
http://dx.doi.org/10.1186/1471-2091-5-15