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Case series of Fournier's gangrene: Affected body surface area – The underestimated prognostic factor

OBJECTIVES: Identifying the factors affecting the outcome of patients with Fournier's Gangrene and assaying the accuracy of the Fournier Gangrene Severity Index (FGIS), the Uludag score (UdS), affected Body Surface Area (BSA) and the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC)...

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Autores principales: Morais, Henrique, Neves, Jessica, Maciel Ribeiro, Hugo, Ferreira, Marta, Guimarães, Narcisa, Azenha, Nuno, Dias, Raquel, Fonseca, Alice, Conceição, Lucilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338720/
https://www.ncbi.nlm.nih.gov/pubmed/28289541
http://dx.doi.org/10.1016/j.amsu.2017.02.043
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author Morais, Henrique
Neves, Jessica
Maciel Ribeiro, Hugo
Ferreira, Marta
Guimarães, Narcisa
Azenha, Nuno
Dias, Raquel
Fonseca, Alice
Conceição, Lucilia
author_facet Morais, Henrique
Neves, Jessica
Maciel Ribeiro, Hugo
Ferreira, Marta
Guimarães, Narcisa
Azenha, Nuno
Dias, Raquel
Fonseca, Alice
Conceição, Lucilia
author_sort Morais, Henrique
collection PubMed
description OBJECTIVES: Identifying the factors affecting the outcome of patients with Fournier's Gangrene and assaying the accuracy of the Fournier Gangrene Severity Index (FGIS), the Uludag score (UdS), affected Body Surface Area (BSA) and the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) model as prognostic tools. MATERIALS AND METHODS: Retrospective study involving all patients with Fournier's gangrene treated in our Hospital between January 2008 and December 2015. The epidemiological, clinical, biochemical and management data of these patients was obtained and analyzed. RESULTS: The series includes 19 patients, 14 male and 5 female, with a median age of 70 (62; 78,5) years. The mortality rate was 21%. From the data analyzed, only the affected BSA (BSA>3.25%) was associated with mortality (p = 0.016). None of the established scores (FGSI; UdS; LRINEC) proved to be a useful tool for predicting mortality. The combination of affected BSA and FSGI (FGSI≥9 or BSA>3.25%), (p = 0.004) and the combination of the affected BSA and the LRINEC model (LRICEC≥8 and BSA>3.25%), (p = 0.004) led to a major improvement in these scores. CONCLUSIONS: Affected BSA is a useful prognostic factor in Fournier's gangrene. The existing prognostic scores can be improved with the introduction of this factor.
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spelling pubmed-53387202017-03-13 Case series of Fournier's gangrene: Affected body surface area – The underestimated prognostic factor Morais, Henrique Neves, Jessica Maciel Ribeiro, Hugo Ferreira, Marta Guimarães, Narcisa Azenha, Nuno Dias, Raquel Fonseca, Alice Conceição, Lucilia Ann Med Surg (Lond) Original Research OBJECTIVES: Identifying the factors affecting the outcome of patients with Fournier's Gangrene and assaying the accuracy of the Fournier Gangrene Severity Index (FGIS), the Uludag score (UdS), affected Body Surface Area (BSA) and the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) model as prognostic tools. MATERIALS AND METHODS: Retrospective study involving all patients with Fournier's gangrene treated in our Hospital between January 2008 and December 2015. The epidemiological, clinical, biochemical and management data of these patients was obtained and analyzed. RESULTS: The series includes 19 patients, 14 male and 5 female, with a median age of 70 (62; 78,5) years. The mortality rate was 21%. From the data analyzed, only the affected BSA (BSA>3.25%) was associated with mortality (p = 0.016). None of the established scores (FGSI; UdS; LRINEC) proved to be a useful tool for predicting mortality. The combination of affected BSA and FSGI (FGSI≥9 or BSA>3.25%), (p = 0.004) and the combination of the affected BSA and the LRINEC model (LRICEC≥8 and BSA>3.25%), (p = 0.004) led to a major improvement in these scores. CONCLUSIONS: Affected BSA is a useful prognostic factor in Fournier's gangrene. The existing prognostic scores can be improved with the introduction of this factor. Elsevier 2017-02-27 /pmc/articles/PMC5338720/ /pubmed/28289541 http://dx.doi.org/10.1016/j.amsu.2017.02.043 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Research
Morais, Henrique
Neves, Jessica
Maciel Ribeiro, Hugo
Ferreira, Marta
Guimarães, Narcisa
Azenha, Nuno
Dias, Raquel
Fonseca, Alice
Conceição, Lucilia
Case series of Fournier's gangrene: Affected body surface area – The underestimated prognostic factor
title Case series of Fournier's gangrene: Affected body surface area – The underestimated prognostic factor
title_full Case series of Fournier's gangrene: Affected body surface area – The underestimated prognostic factor
title_fullStr Case series of Fournier's gangrene: Affected body surface area – The underestimated prognostic factor
title_full_unstemmed Case series of Fournier's gangrene: Affected body surface area – The underestimated prognostic factor
title_short Case series of Fournier's gangrene: Affected body surface area – The underestimated prognostic factor
title_sort case series of fournier's gangrene: affected body surface area – the underestimated prognostic factor
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338720/
https://www.ncbi.nlm.nih.gov/pubmed/28289541
http://dx.doi.org/10.1016/j.amsu.2017.02.043
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