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Case series of Fournier's gangrene: Affected body surface area – The underestimated prognostic factor
OBJECTIVES: Identifying the factors affecting the outcome of patients with Fournier's Gangrene and assaying the accuracy of the Fournier Gangrene Severity Index (FGIS), the Uludag score (UdS), affected Body Surface Area (BSA) and the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC)...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338720/ https://www.ncbi.nlm.nih.gov/pubmed/28289541 http://dx.doi.org/10.1016/j.amsu.2017.02.043 |
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author | Morais, Henrique Neves, Jessica Maciel Ribeiro, Hugo Ferreira, Marta Guimarães, Narcisa Azenha, Nuno Dias, Raquel Fonseca, Alice Conceição, Lucilia |
author_facet | Morais, Henrique Neves, Jessica Maciel Ribeiro, Hugo Ferreira, Marta Guimarães, Narcisa Azenha, Nuno Dias, Raquel Fonseca, Alice Conceição, Lucilia |
author_sort | Morais, Henrique |
collection | PubMed |
description | OBJECTIVES: Identifying the factors affecting the outcome of patients with Fournier's Gangrene and assaying the accuracy of the Fournier Gangrene Severity Index (FGIS), the Uludag score (UdS), affected Body Surface Area (BSA) and the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) model as prognostic tools. MATERIALS AND METHODS: Retrospective study involving all patients with Fournier's gangrene treated in our Hospital between January 2008 and December 2015. The epidemiological, clinical, biochemical and management data of these patients was obtained and analyzed. RESULTS: The series includes 19 patients, 14 male and 5 female, with a median age of 70 (62; 78,5) years. The mortality rate was 21%. From the data analyzed, only the affected BSA (BSA>3.25%) was associated with mortality (p = 0.016). None of the established scores (FGSI; UdS; LRINEC) proved to be a useful tool for predicting mortality. The combination of affected BSA and FSGI (FGSI≥9 or BSA>3.25%), (p = 0.004) and the combination of the affected BSA and the LRINEC model (LRICEC≥8 and BSA>3.25%), (p = 0.004) led to a major improvement in these scores. CONCLUSIONS: Affected BSA is a useful prognostic factor in Fournier's gangrene. The existing prognostic scores can be improved with the introduction of this factor. |
format | Online Article Text |
id | pubmed-5338720 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-53387202017-03-13 Case series of Fournier's gangrene: Affected body surface area – The underestimated prognostic factor Morais, Henrique Neves, Jessica Maciel Ribeiro, Hugo Ferreira, Marta Guimarães, Narcisa Azenha, Nuno Dias, Raquel Fonseca, Alice Conceição, Lucilia Ann Med Surg (Lond) Original Research OBJECTIVES: Identifying the factors affecting the outcome of patients with Fournier's Gangrene and assaying the accuracy of the Fournier Gangrene Severity Index (FGIS), the Uludag score (UdS), affected Body Surface Area (BSA) and the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) model as prognostic tools. MATERIALS AND METHODS: Retrospective study involving all patients with Fournier's gangrene treated in our Hospital between January 2008 and December 2015. The epidemiological, clinical, biochemical and management data of these patients was obtained and analyzed. RESULTS: The series includes 19 patients, 14 male and 5 female, with a median age of 70 (62; 78,5) years. The mortality rate was 21%. From the data analyzed, only the affected BSA (BSA>3.25%) was associated with mortality (p = 0.016). None of the established scores (FGSI; UdS; LRINEC) proved to be a useful tool for predicting mortality. The combination of affected BSA and FSGI (FGSI≥9 or BSA>3.25%), (p = 0.004) and the combination of the affected BSA and the LRINEC model (LRICEC≥8 and BSA>3.25%), (p = 0.004) led to a major improvement in these scores. CONCLUSIONS: Affected BSA is a useful prognostic factor in Fournier's gangrene. The existing prognostic scores can be improved with the introduction of this factor. Elsevier 2017-02-27 /pmc/articles/PMC5338720/ /pubmed/28289541 http://dx.doi.org/10.1016/j.amsu.2017.02.043 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Research Morais, Henrique Neves, Jessica Maciel Ribeiro, Hugo Ferreira, Marta Guimarães, Narcisa Azenha, Nuno Dias, Raquel Fonseca, Alice Conceição, Lucilia Case series of Fournier's gangrene: Affected body surface area – The underestimated prognostic factor |
title | Case series of Fournier's gangrene: Affected body surface area – The underestimated prognostic factor |
title_full | Case series of Fournier's gangrene: Affected body surface area – The underestimated prognostic factor |
title_fullStr | Case series of Fournier's gangrene: Affected body surface area – The underestimated prognostic factor |
title_full_unstemmed | Case series of Fournier's gangrene: Affected body surface area – The underestimated prognostic factor |
title_short | Case series of Fournier's gangrene: Affected body surface area – The underestimated prognostic factor |
title_sort | case series of fournier's gangrene: affected body surface area – the underestimated prognostic factor |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338720/ https://www.ncbi.nlm.nih.gov/pubmed/28289541 http://dx.doi.org/10.1016/j.amsu.2017.02.043 |
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