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The brain-specific RasGEF very-KIND is required for normal dendritic growth in cerebellar granule cells and proper motor coordination

Very-KIND/Kndc1/KIAA1768 (v-KIND) is a brain-specific Ras guanine nucleotide exchange factor carrying two sets of the kinase non-catalytic C-lobe domain (KIND), and is predominantly expressed in cerebellar granule cells. Here, we report the impact of v-KIND deficiency on dendritic and synaptic growt...

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Detalles Bibliográficos
Autores principales: Hayashi, Kanehiro, Furuya, Asako, Sakamaki, Yuriko, Akagi, Takumi, Shinoda, Yo, Sadakata, Tetsushi, Hashikawa, Tsutomu, Shimizu, Kazuki, Minami, Haruka, Sano, Yoshitake, Nakayama, Manabu, Furuichi, Teiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338823/
https://www.ncbi.nlm.nih.gov/pubmed/28264072
http://dx.doi.org/10.1371/journal.pone.0173175