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Both anti-TNF and CTLA4 Ig treatments attenuate the disease severity of staphylococcal dermatitis in mice

BACKGROUND: RA patients being treated with biologics are known to have an increased risk of infections. We recently demonstrated that both CTLA4 Ig and anti-TNF treatment aggravate systemic Staphylococcus aureus (S. aureus) infection in mice, but with distinct clinical manifestations. However, the e...

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Detalles Bibliográficos
Autores principales: Na, Manli, Wang, Wanzhong, Fei, Ying, Josefsson, Elisabet, Ali, Abukar, Jin, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338833/
https://www.ncbi.nlm.nih.gov/pubmed/28264025
http://dx.doi.org/10.1371/journal.pone.0173492