Transcriptional profiling identifies the long noncoding RNA plasmacytoma variant translocation (PVT1) as a novel regulator of the asthmatic phenotype in human airway smooth muscle

BACKGROUND: The mechanism underlying nonsevere and severe asthma remains unclear, although it is commonly associated with increased airway smooth muscle (ASM) mass. Long noncoding RNAs (lncRNAs) are known to be important in regulating healthy primary airway smooth muscle cells (ASMCs), whereas chang...

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Detalles Bibliográficos
Autores principales: Austin, Philip J., Tsitsiou, Eleni, Boardman, Charlotte, Jones, Simon W., Lindsay, Mark A., Adcock, Ian M., Chung, Kian Fan, Perry, Mark M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mosby 2017
Materias:
Asthma and Lower Airway Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338875/
https://www.ncbi.nlm.nih.gov/pubmed/27484035
http://dx.doi.org/10.1016/j.jaci.2016.06.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338875/
https://www.ncbi.nlm.nih.gov/pubmed/27484035
http://dx.doi.org/10.1016/j.jaci.2016.06.014

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