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Impact of caspase-1/11, -3, -7, or IL-1β/IL-18 deficiency on rabies virus-induced macrophage cell death and onset of disease

Rabies virus is a highly neurovirulent RNA virus, which causes about 59000 deaths in humans each year. Previously, we described macrophage cytotoxicity upon infection with rabies virus. Here we examined the type of cell death and the role of specific caspases in cell death and disease development up...

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Detalles Bibliográficos
Autores principales:	Kip, E, Nazé, F, Suin, V, Vanden Berghe, T, Francart, A, Lamoral, S, Vandenabeele, P, Beyaert, R, Van Gucht, S, Kalai, M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339016/ https://www.ncbi.nlm.nih.gov/pubmed/28280602 http://dx.doi.org/10.1038/cddiscovery.2017.12

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