Synthetic mimetics of the endogenous gastrointestinal nanomineral: Silent constructs that trap macromolecules for intracellular delivery

Amorphous magnesium-substituted calcium phosphate (AMCP) nanoparticles (75-150 nm) form constitutively in large numbers in the mammalian gut. Collective evidence indicates that they trap and deliver luminal macromolecules to mucosal antigen presenting cells (APCs) and facilitate gut immune homeostas...

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Detalles Bibliográficos
Autores principales: Pele, Laetitia C., Haas, Carolin T., Hewitt, Rachel E., Robertson, Jack, Skepper, Jeremy, Brown, Andy, Hernandez-Garrido, Juan Carlos, Midgley, Paul A., Faria, Nuno, Chappell, Helen, Powell, Jonathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339085/
https://www.ncbi.nlm.nih.gov/pubmed/27478107
http://dx.doi.org/10.1016/j.nano.2016.07.008

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