PilY1 Promotes Legionella pneumophila Infection of Human Lung Tissue Explants and Contributes to Bacterial Adhesion, Host Cell Invasion, and Twitching Motility

Legionnaires' disease is an acute fibrinopurulent pneumonia. During infection Legionella pneumophila adheres to the alveolar lining and replicates intracellularly within recruited macrophages. Here we provide a sequence and domain composition analysis of the L. pneumophila PilY1 protein, which...

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Detalles Bibliográficos
Autores principales: Hoppe, Julia, Ünal, Can M., Thiem, Stefanie, Grimpe, Louisa, Goldmann, Torsten, Gaßler, Nikolaus, Richter, Matthias, Shevchuk, Olga, Steinert, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339237/
https://www.ncbi.nlm.nih.gov/pubmed/28326293
http://dx.doi.org/10.3389/fcimb.2017.00063

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