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Disease Risk Assessment Using a Voronoi-Based Network Analysis of Genes and Variants Scores

Much effort has been devoted to assess disease risk based on large-scale protein-protein network and genotype-phenotype associations. However, the challenge of risk prediction for complex diseases remains unaddressed. Here, we propose a framework to quantify the risk based on a Voronoi tessellation...

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Detalles Bibliográficos
Autores principales: Chen, Lin, Mukerjee, Gouri, Dorfman, Ruslan, Moghadas, Seyed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339255/
https://www.ncbi.nlm.nih.gov/pubmed/28326099
http://dx.doi.org/10.3389/fgene.2017.00029