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Disease Risk Assessment Using a Voronoi-Based Network Analysis of Genes and Variants Scores
Much effort has been devoted to assess disease risk based on large-scale protein-protein network and genotype-phenotype associations. However, the challenge of risk prediction for complex diseases remains unaddressed. Here, we propose a framework to quantify the risk based on a Voronoi tessellation...
Autores principales: | Chen, Lin, Mukerjee, Gouri, Dorfman, Ruslan, Moghadas, Seyed M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339255/ https://www.ncbi.nlm.nih.gov/pubmed/28326099 http://dx.doi.org/10.3389/fgene.2017.00029 |
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