Cargando…

Microbial Neuraminidase Induces a Moderate and Transient Myelin Vacuolation Independent of Complement System Activation

AIMS: Some central nervous system pathogens express neuraminidase (NA) on their surfaces. In the rat brain, a single intracerebroventricular (ICV) injection of NA induces myelin vacuolation in axonal tracts. Here, we explore the nature, the time course, and the role of the complement system in this...

Descripción completa

Detalles Bibliográficos
Autores principales:	Granados-Durán, Pablo, López-Ávalos, María Dolores, Cifuentes, Manuel, Pérez-Martín, Margarita, Fernández-Arjona, María del Mar, Hughes, Timothy R., Johnson, Krista, Morgan, B. Paul, Fernández-Llebrez, Pedro, Grondona, Jesús M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339270/ https://www.ncbi.nlm.nih.gov/pubmed/28326060 http://dx.doi.org/10.3389/fneur.2017.00078

Ejemplares similares

Complement system activation contributes to the ependymal damage induced by microbial neuraminidase
por: Granados-Durán, Pablo, et al.
Publicado: (2016)

Microglial activation by microbial neuraminidase through TLR2 and TLR4 receptors
por: Fernández-Arjona, María del Mar, et al.
Publicado: (2019)

Neuroinflammation Induced by Intracerebroventricular Injection of Microbial Neuraminidase
por: Granados-Durán, Pablo, et al.
Publicado: (2015)

Microglia activated by microbial neuraminidase contributes to ependymal cell death
por: Fernández-Arjona, María del Mar, et al.
Publicado: (2021)

Microglia Morphological Categorization in a Rat Model of Neuroinflammation by Hierarchical Cluster and Principal Components Analysis
por: Fernández-Arjona, María del Mar, et al.
Publicado: (2017)

Microbial neuraminidase induces TLR4-dependent long-term immune priming in the brain
por: Fernández-Arjona, María del Mar, et al.
Publicado: (2022)

Microglial Morphometric Parameters Correlate With the Expression Level of IL-1β, and Allow Identifying Different Activated Morphotypes
por: Fernández-Arjona, María del Mar, et al.
Publicado: (2019)

Anxiety-like behavior and microglial activation in the amygdala after acute neuroinflammation induced by microbial neuraminidase
por: León-Rodríguez, Ana, et al.
Publicado: (2022)

Pharmacological Administration of the Isoflavone Daidzein Enhances Cell Proliferation and Reduces High Fat Diet-Induced Apoptosis and Gliosis in the Rat Hippocampus
por: Rivera, Patricia, et al.
Publicado: (2013)

Long‐term priming of hypothalamic microglia is associated with energy balance disturbances under diet‐induced obesity
por: Fernández‐Arjona, María del Mar, et al.
Publicado: (2022)

Cuprizone Intoxication Results in Myelin Vacuole Formation
por: Joost, Sarah, et al.
Publicado: (2022)

Antibody-independent complement activation by myelin via the classical complement pathway
Publicado: (1982)

Dissection of complement and Fc-receptor-mediated pathomechanisms of autoantibodies to myelin oligodendrocyte glycoprotein
por: Mader, Simone, et al.
Publicado: (2023)

Structure and function of the ependymal barrier and diseases associated with ependyma disruption
por: Jiménez, Antonio J, et al.
Publicado: (2014)

Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders
por: Mader, Simone, et al.
Publicado: (2011)

Human Sperm Head Vacuoles Are Related to Nuclear-Envelope Invaginations
por: Gómez-Torres, María José, et al.
Publicado: (2023)

Complement-dependent cytotoxicity of human autoantibodies against myelin oligodendrocyte glycoprotein
por: Kohyama, Kuniko, et al.
Publicado: (2023)

Influenza neuraminidase
por: Air, Gillian M.
Publicado: (2011)

Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design
por: Zhu, Qinchang, et al.
Publicado: (2015)

Microglia phagocytose myelin sheaths to modify developmental myelination
por: Hughes, Alexandria N., et al.
Publicado: (2020)

A neuraminidase potency assay for quantitative assessment of neuraminidase in influenza vaccines
por: Byrne-Nash, Rose T., et al.
Publicado: (2019)

Consecutive influenza surveillance of neuraminidase mutations and neuraminidase inhibitor resistance in Japan
por: Chong, Yong, et al.
Publicado: (2019)

Neuraminidase B controls neuraminidase A-dependent mucus production and evasion
por: Hammond, Alexandria J., et al.
Publicado: (2021)

Regulation of developing myelin sheath elongation by oligodendrocyte calcium transients in vivo
por: Krasnow, Anna M., et al.
Publicado: (2017)

Etymologia: Hemagglutinin and Neuraminidase
por: Henry, Ronnie, et al.
Publicado: (2018)

Transient expression of fusion and hemagglutinin-neuraminidase epitopes of Newcastle disease virus in maize as a potent candidate vaccine
por: Shahriari, Amir Ghaffar, et al.
Publicado: (2021)

More Efficient Complement Activation by Anti–Aquaporin-4 Compared With Anti–Myelin Oligodendrocyte Glycoprotein Antibodies
por: Lerch, Magdalena, et al.
Publicado: (2022)

Human antibodies against the myelin oligodendrocyte glycoprotein can cause complement-dependent demyelination
por: Peschl, Patrick, et al.
Publicado: (2017)

Myelin-specific multiple sclerosis antibodies cause complement-dependent oligodendrocyte loss and demyelination
por: Liu, Yiting, et al.
Publicado: (2017)

The R1-weighted connectome: complementing brain networks with a myelin-sensitive measure
por: Boshkovski, Tommy, et al.
Publicado: (2021)

Bacterial Neuraminidase Rescues Influenza Virus Replication from Inhibition by a Neuraminidase Inhibitor
por: Nishikawa, Tomoko, et al.
Publicado: (2012)

The cAMP effectors, Rap2b and EPAC, are involved in the regulation of the development of the Coxiella burnetii containing vacuole by altering the fusogenic capacity of the vacuole
por: Mansilla Pareja, María Eugenia, et al.
Publicado: (2019)

An Electron Microscope Study of the Contractile Vacuole in Tokophrya infusionum
por: Rudzinska, Maria A.
Publicado: (1958)

At the Nexus between Cytoskeleton and Vacuole: How Plant Cytoskeletons Govern the Dynamics of Large Vacuoles
por: Takatsuka, Hirotomo, et al.
Publicado: (2023)

Copine A, a calcium-dependent membrane-binding protein, transiently localizes to the plasma membrane and intracellular vacuoles in Dictyostelium
por: Damer, Cynthia K, et al.
Publicado: (2005)

EhVps32 Is a Vacuole-Associated Protein Involved in Pinocytosis and Phagocytosis of Entamoeaba histolytica
por: Avalos-Padilla, Yunuen, et al.
Publicado: (2015)

Transient perturbation of endothelial integrity induced by natural antibodies and complement
Publicado: (1995)

The proteolytic landscape of the yeast vacuole
por: Hecht, Karen A, et al.
Publicado: (2014)

Calcium Signals from the Vacuole
por: Schönknecht, Gerald
Publicado: (2013)

Multinodular and Vacuolating Neuronal Tumor
por: Zahra, Charmaine, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_olvt7oah7tedeh0l8ermhq7if1