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Characterization of the Highly Prevalent Regulatory CD24(hi)CD38(hi) B-Cell Population in Human Cord Blood
The newborn’s immune system must transition from a sterile haploidentical uterus to the world full of antigens. Regulatory B-cells (Breg; broadly defined as CD19(+)CD24(hi)CD38(hi)) are tolerance promoters in the adult immune system. They can inhibit IFN-γ and IL-17 production by T-cells and are ess...
Autores principales: | Esteve-Solé, Ana, Teixidó, Irene, Deyà-Martínez, Angela, Yagüe, Jordi, Plaza-Martín, Ana M., Juan, Manel, Alsina, Laia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339297/ https://www.ncbi.nlm.nih.gov/pubmed/28326080 http://dx.doi.org/10.3389/fimmu.2017.00201 |
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