The Small Tellurium Compound AS101 Ameliorates Rat Crescentic Glomerulonephritis: Association with Inhibition of Macrophage Caspase-1 Activity via Very Late Antigen-4 Inactivation

Crescentic glomerulonephritis (CGN) is the most aggressive form of GN and, if untreated, patients can progress to end-stage renal failure within weeks of presentation. The α4β1 integrin very late antigen-4 (VLA-4) is an adhesion molecule of fundamental importance to the recruitment of leukocytes in...

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Detalles Bibliográficos
Autores principales: Hachmo, Yafit, Kalechman, Yona, Skornick, Itai, Gafter, Uzi, Caspi, Rachel R., Sredni, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339302/
https://www.ncbi.nlm.nih.gov/pubmed/28326083
http://dx.doi.org/10.3389/fimmu.2017.00240

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