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Pre-Clinical Studies with D-Penicillamine as a Novel Pharmacological Strategy to Treat Alcoholism: Updated Evidences

Ethanol, as other drugs of abuse, is able to activate the ventral tegmental area dopamine (VTA-DA) neurons leading to positively motivational alcohol-seeking behavior and use, and, ultimately to ethanol addiction. In the last decades, the involvement of brain-derived acetaldehyde (ACD) in the ethano...

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Detalles Bibliográficos
Autores principales: Orrico, Alejandro, Martí-Prats, Lucía, Cano-Cebrián, María J., Granero, Luis, Polache, Ana, Zornoza, Teodoro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339308/
https://www.ncbi.nlm.nih.gov/pubmed/28326026
http://dx.doi.org/10.3389/fnbeh.2017.00037