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Localized redox relays as a privileged mode of cytoplasmic hydrogen peroxide signaling
Hydrogen peroxide (H(2)O(2)) is a key signaling agent. Its best characterized signaling actions in mammalian cells involve the early oxidation of thiols in cytoplasmic phosphatases, kinases and transcription factors. However, these redox targets are orders of magnitude less H(2)O(2)-reactive and abu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339411/ https://www.ncbi.nlm.nih.gov/pubmed/28279943 http://dx.doi.org/10.1016/j.redox.2017.01.003 |