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Mutagenic and Cytotoxicity LQB 123 Profile: Safety and Tripanocidal Effect of a Phenyl-t-Butylnitrone Derivative

The therapeutic options for Chagas disease are limited and its treatment presents a number of drawbacks including toxicity, drug resistance, and insufficient effectiveness against the chronic stage of the disease. Therefore, new therapeutical options are mandatory. In the present work, we evaluated...

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Detalles Bibliográficos
Autores principales: Cupello, Mauricio Peixoto, Saraiva, Francis Monique, Ippolito, Pedro, Fernandes, Andréia da Silva, Menna-Barreto, Rubem Figueiredo Sadoko, Costa, Debora de Sousa dos Santos, Paula, Jessica Isis Oliveira, Costa, Paulo Roberto Ribeiro, Nogueira, Natália Pereira, Felzenswalb, Israel, Dias, Ayres Guimarães, Paes, Marcia Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339480/
https://www.ncbi.nlm.nih.gov/pubmed/28316976
http://dx.doi.org/10.1155/2017/2483652