Identification of Significant Pathways Induced by PAX5 Haploinsufficiency Based on Protein-Protein Interaction Networks and Cluster Analysis in Raji Cell Line

PAX5 encodes a transcription factor essential for B-cell differentiation, and PAX5 haploinsufficiency is involved in tumorigenesis. There were few studies on how PAX5 haploinsufficiency regulated genes expression to promote tumorigenesis. In this study, we constructed the cell model of PAX5 haploins...

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Detalles Bibliográficos
Autores principales: Gu, Jia, Li, TongJuan, Zhao, Lei, Liang, Xue, Fu, Xing, Wang, Jue, Shang, Zhen, Huang, Wei, Zhou, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339483/
https://www.ncbi.nlm.nih.gov/pubmed/28316978
http://dx.doi.org/10.1155/2017/5326370

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