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Salivary Distinctiveness and Modifications in Males with Diabetes and Behçet's Disease

Oral diseases associated with systematic diseases as metabolic and vasculitic have been included in this paper. This will enhance our understanding of the salivary function in promoting healthy oral condition. The study investigates the effects of type I and type II diabetes mellitus in well-control...

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Autores principales: Aljerf, Loai, Alhaffar, Iyad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339495/
https://www.ncbi.nlm.nih.gov/pubmed/28321337
http://dx.doi.org/10.1155/2017/9596202
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author Aljerf, Loai
Alhaffar, Iyad
author_facet Aljerf, Loai
Alhaffar, Iyad
author_sort Aljerf, Loai
collection PubMed
description Oral diseases associated with systematic diseases as metabolic and vasculitic have been included in this paper. This will enhance our understanding of the salivary function in promoting healthy oral condition. The study investigates the effects of type I and type II diabetes mellitus in well-controlled diabetic patients, in addition to Behçet disease (BD) on saliva flow rate (SFR), pH, the decay, missing, and filled tooth (DMFT) index, glucose, and major earth-alkaline ions (Ca(2+) and Mg(2+)) compared to healthy males and age-matched controls. Saliva samples were collected from 1403 male human subjects, distributed on 7 levels including 3 control groups, and analyzed. The symptoms and clinical observations were enrolled. A preprandial salivary glucose has illustrated statistically strong significant and positive correlations with HbA(1c) and blood glucose levels. TIDM saliva showed lower pH, SFR, and Ca(2+) but higher Mg(2+), caries risk, and poor metabolic control. These led to dysfunction of secretory capacity of salivary glands. TIIDM proved higher SFR, DMFT, and glucose than TIDM patients. DM oral calcium has decreased by age while magnesium sharply slopes at seniority. BD oral fluid is associated with lower glucose and minerals but noticeably with both higher pH and DMFT.
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spelling pubmed-53394952017-03-20 Salivary Distinctiveness and Modifications in Males with Diabetes and Behçet's Disease Aljerf, Loai Alhaffar, Iyad Biochem Res Int Research Article Oral diseases associated with systematic diseases as metabolic and vasculitic have been included in this paper. This will enhance our understanding of the salivary function in promoting healthy oral condition. The study investigates the effects of type I and type II diabetes mellitus in well-controlled diabetic patients, in addition to Behçet disease (BD) on saliva flow rate (SFR), pH, the decay, missing, and filled tooth (DMFT) index, glucose, and major earth-alkaline ions (Ca(2+) and Mg(2+)) compared to healthy males and age-matched controls. Saliva samples were collected from 1403 male human subjects, distributed on 7 levels including 3 control groups, and analyzed. The symptoms and clinical observations were enrolled. A preprandial salivary glucose has illustrated statistically strong significant and positive correlations with HbA(1c) and blood glucose levels. TIDM saliva showed lower pH, SFR, and Ca(2+) but higher Mg(2+), caries risk, and poor metabolic control. These led to dysfunction of secretory capacity of salivary glands. TIIDM proved higher SFR, DMFT, and glucose than TIDM patients. DM oral calcium has decreased by age while magnesium sharply slopes at seniority. BD oral fluid is associated with lower glucose and minerals but noticeably with both higher pH and DMFT. Hindawi Publishing Corporation 2017 2017-02-21 /pmc/articles/PMC5339495/ /pubmed/28321337 http://dx.doi.org/10.1155/2017/9596202 Text en Copyright © 2017 Loai Aljerf and Iyad Alhaffar. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Aljerf, Loai
Alhaffar, Iyad
Salivary Distinctiveness and Modifications in Males with Diabetes and Behçet's Disease
title Salivary Distinctiveness and Modifications in Males with Diabetes and Behçet's Disease
title_full Salivary Distinctiveness and Modifications in Males with Diabetes and Behçet's Disease
title_fullStr Salivary Distinctiveness and Modifications in Males with Diabetes and Behçet's Disease
title_full_unstemmed Salivary Distinctiveness and Modifications in Males with Diabetes and Behçet's Disease
title_short Salivary Distinctiveness and Modifications in Males with Diabetes and Behçet's Disease
title_sort salivary distinctiveness and modifications in males with diabetes and behçet's disease
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339495/
https://www.ncbi.nlm.nih.gov/pubmed/28321337
http://dx.doi.org/10.1155/2017/9596202
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