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Cellular Dynamics of Rad51 and Rad54 in Response to Postreplicative Stress and DNA Damage in HeLa Cells

Homologous recombination (HR) is necessary for maintenance of genomic integrity and prevention of various mutations in tumor suppressor genes and proto-oncogenes. Rad51 and Rad54 are key HR factors that cope with replication stress and DNA breaks in eukaryotes. Rad51 binds to single-stranded DNA (ss...

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Detalles Bibliográficos
Autores principales: Choi, Eui-Hwan, Yoon, Seobin, Hahn, Yoonsoo, Kim, Keun P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339505/
https://www.ncbi.nlm.nih.gov/pubmed/28190324
http://dx.doi.org/10.14348/molcells.2017.2275